Lepore et al. demonstrated significant upregulation of the protein fragment of BARD1 between exons 6 and 11, corresponding to the FL, α, β, κ, and π isoforms, in AML patient blasts and in AML cell lines, NB4, U937, K562, and HL60 [17]. This evidence concerns the gene BARD1 and acute myeloid leukemia.