TAS2R38 and congenital rubella syndrome: Cantone et al. confirmed that the nonfunctional genotype is more frequent among CRS patients than in the general population (25% vs.18.4%), that airway Gram negative infections are primarily associated with AVI and that biofilm formation is prevalent in CRS patients with the AVI nontaster phenotype, which confirmed an inverse correlation between TAS2R38 functionality and Gram negative infections in patients with CRSwNP [74,75].