Other possible explanations for the higher detection rate of [18F]Fluorocholine PET/CT compared to [68Ga]Ga-PSMA PET/CT include the superiority of [18F]Fluorocholine PET/CT in the detection of bone metastases in poorly differentiated prostate cancers, and its ability to detect extra nodes that have begun the process of dedifferentiation [30,31,32]. This evidence concerns the gene FOLH1 and Familial prostate cancer.