The authors of this study considered different covariates in their evaluations, such as age, sex, BMI, years of education, and APOE ε4 status, and the results they obtained suggested that ALT and AST to ALT ratio, whose levels increased in NAFLD patients, were directly associated with poor cognition and greater Aβ deposition in brain areas [35]. This evidence concerns the gene GPT and metabolic dysfunction-associated steatotic liver disease.