In bladder cancer, Y-Box Binding Protein 1 (YBX1) has been identified as a an m5C “reader” and was shown to promote carcinogenesis by stabilizing Hepatoma-Derived Growth Factor (HDGF) through an interaction with Elav-Like RNA-Binding Protein 1 (ELAVL1). Here, HDGF is linked to urinary bladder carcinoma.