ERBB2 and breast cancer: We have also shown that miR526b and miR655 overexpression in ER-positive breast cancer cell line MCF7 and an ER-negative HER2-positive breast cancer cell line SKBR3 promotes epithelial-to-mesenchymal transition (EMT), cell migration, invasion, induction of stem-like cells (SLCs) phenotype, tumor growth, and metastasis in vivo [13,14].