To further investigate the tumor suppressive properties of FGF14 in vivo, we used a NOD. Cg-Prkdcscid Il2rgtm1Wjl/SzJ xenograft model and observed approximately 65 % reduction in tumor volume and mass in FGF14 overexpressing tumors compared with the control tumors. The gene discussed is FGF14; the disease is neoplasm.