To investigate the tumor suppressive properties of FGF14 overexpressing cells in vivo, we transplanted A549-FGF14 OE and A549-EV cells subcutaneously into the right flank of NOD. Cg-Prkdcscid Il2rgtm1Wjl/SzJ (NSG) immunodeficient mice. This evidence concerns the gene FGF14 and neoplasm.