The results confirmed that DEHP could induce atherosclerosis by significantly increasing MMP-2 and MMP-9 expression through the regulation of different pathways, including p38 mitogen-activated protein kinase (MAPK), extracellular signal regulated kinase 1 and 2 (ERK1/2), Akt, and nuclear factor-kappaB (NF-κB) [39]. The gene discussed is MMP9; the disease is atherosclerosis.