CXCL12 and Burkitt lymphoma: Tino et al. presented that fucoidan bound to CXCL12 and interfered the CXCL12/CXCR4 axis in human Burkitt’s lymphoma cells, thereby blocking both CXCL12-induced CXCR4 receptor activation and downstream effects, such as migration and matrix metalloproteinase-9 secretion (Table 1) [53].