However, while the aggregation of Aβ (1–40) was suppressed by the αAC nanofiber, that of the fragment comprising the three-repeats of a microtubule-binding domain (3RMBD) of tau protein was promoted; this is remarkably unfavorable for developing the therapeutic peptide nanofibers for the treatment of AD because both proteins are AD-related [29]. Here, MAPT is linked to Alzheimer disease.