However, there are some limitations in the present study, for instance, future work may be required to investigate whether the expression profiles of hsa_circRNA_102209, miR‐761 and RIN1 are differentiated between CRC cases with metastasis to other organs and non‐metastatic group, if so, this novel signaling could also be with therapeutic usefulness for the treatment of metastatic cases to other organs. This evidence concerns the gene RIN1 and colorectal carcinoma.