The association between BGU and insulin secretion was driven by the non‐diabetic subjects, because when we divided the data set into two groups T2D (N = 15) and non‐T2D (N = 52), it remained significant only in the non‐T2D (r = 0.51, P = .0008 for basal ISR, and r = 0.51, P = .0008 for total insulin output) (Figure 1). This evidence concerns the gene INS and type 2 diabetes mellitus.