Mefenamic acid is known to provide significant protection against elevated levels of TNF-α and IL-1β in radiation-induced genotoxicity of human lymphocytes (Armagan et al., 2012; Hosseinimehr et al., 2015); furosemide is known to significantly reduce production of IL-6, IL-8 and TNF-α in bronchial inflammation of asthma (Prandota, 2002; Yuengsrigul, Chin & Nussbaum, 1999). The gene discussed is TNF; the disease is asthma.