MMP8 and gastric cancer: Particularly, MMP-8 and -9 and TIMP-1 were found to be significantly upregulated in 90%, 80%, and 70% of GC patients, respectively.13 Subsequently, Puig-Costa et al. identified 21 GC-associated inflammatory proteins (including MMP-8 and -9 and TIMP-1) in another cohort of matched pairs (n=10) using antibody microarray-based arrays.