This finding is of particular interest because EGFR phosphorylation at Ser1070 plays a critical role in EGFR desensitisation, internalisation and degradation.21,22 To further study the role of PGRMC1 in breast cancers, we analysed clinical data from TCGA–BRCA datasets (https://xenabrowser.net). The gene discussed is EGFR; the disease is breast cancer.