TP53 and neoplasm: However, a positive association between miR-34a and β-catenin, due to well-known oncogenic function of β-catenin as a co-transcriptional factor in Wnt/β-catenin signaling pathway, and common tumor suppressor function of miR-34a in majority of cancers, seems to be related to a little known mechanism, probably independent of p53 pathway.