A previous study of 217 patients with diabetes showed that patients with comorbidity of hypertension, coronary heart disease, microalbuminuria, or proteinuria had a statistically significant increased level of Lp(a); while the patients with hyper-Lp(a) (≥30 mg/dl) presented significantly increased levels of urea and TC (27). The gene discussed is LPA; the disease is hypertensive disorder.