Similarly, the association between higher Lp(a) concentrations and the incidence of reduced renal function also achieved the most significant results in the group with high Lp(a) and hypertension with ORs of 4.71 (95% CI 2.19–10.15, P < 0.0001; model 1) and 3.09 (95% CI 1.31–7.29, P = 0.01; model 2; Table 3). The gene discussed is LPA; the disease is hypertensive disorder.