GSTM1 and glaucoma: However, Laguna ONhE program can be used in patients that either because of their low visual acuity or their age are not able to maintain their sight in a pre-established fixation point, since the analysis of the amount of ONH Hb only requires a good quality retinography, even if the image of the papilla is off-centre, as we have already demonstrated in previous studies carried out on patients with greater difficulties such as those suffering from childhood glaucoma.