Studies have shown that PSMA enzymatic activity is involved malignancy-driven neoangiogenesis and is expressed in the endothelium of tumor-associated neovasculature of breast, lung, thyroid, hepatocellular carcinoma (HCC), transitional cell carcinoma of the urinary bladder, and a small portion of prostate adenocarcinoma [6, 7]. This evidence concerns the gene FOLH1 and prostate adenocarcinoma.