Mutations associated with LVNC have been reported in more than 40 human genes, including genes encoding for sarcomeric (MYBPC3, MYH7), ion channel (SCN5A, HCN4), cytoskeletal (LDB3/Cypher/ZASP, LMNA), and chaperon proteins [2, 8, 9]. The gene discussed is LDB3; the disease is left ventricular noncompaction.