IL10 and anemia (phenotype): Many strategies have based their research on the use of IL-10 due to its anti-inflammatory properties and key role in the development of the disease, as evidenced by IL-10−/− mice, which develop enterocolitis, a severe disease in the colon characterized by weight loss, anemia and strong inflammatory lesions, apparent already at 4 weeks of age and lethal up to the age of 3 months, when maintained under conventional conditions [4].