This is in agreement with earlier reports that LVEF of <40% is an independent predictor of mortality after MI.[26] Our data further strengthens the importance of addressing timely treatment of heart failure with reduced LVEF, as implantable cardioverter-defibrillator and pharmacologic interventions with agents such as angiotensin-converting enzyme inhibitors and β-blockers may significantly increase survival rate of MI patients.[27]. Here, ACE is linked to heart failure.