An increase in thymidine phosphorylase levels may be associated with a poor prognosis in various solid tumor tissues.[30] Thrombocytosis with a negative prognostic value in lung cancer has been reported before.[31] However, no study has found that higher platelet count is associated with a poorer prognosis in only lung adenocarcinoma with EGFR mutations under TKI treatment. Here, EGFR is linked to thrombocytosis disease.