ALK and anaplastic large cell lymphoma: Immunohistochemistry: GFAP (−), LCA (+), NSE (−), Ki-67 (about 50% in the hot spot area), langerin (−), S-100 (−), CD1 α (−), CD163 (histiocyte + +), CD3 (focus+), cd450ro (+), cxcl-13 (−), PD-1 (scattered +), CD21 (−), CD2 (+), CD5 (+), CD7 (+), CD4 (+), CD8 (+), CD30 (+), ALK (+), EMA (focus +), CD15 (−), CD79a (−), CD20 (−), non-Hodgkin lymphoma, T-cell-derived ALCL, ALK-positive, and pathological immunohistochemistry as shown in Figure 3.