BPGM, PGAM2, PSPH, and ACOT7 were upregulated in HCC, while AGXT, AGXT2, CBS, CTH, DAO, PGAM1, PGAM4, SHMT1, and SHMT2 were downregulated in HCC (Figure 4F). This evidence concerns the gene BPGM and hepatocellular carcinoma.