The Cancer Genome Atlas (TCGA) database found that Succinate CoA ligase subunit alpha (SUCLG1), Phosphoenolpyruvate carboxykinase (PCK2) and Glycine dehydrogenase (GLDC) were differentially expressed in renal cancer, however, there is no scientific research that showed whether they are the oncogenic molecules in renal cancer. Here, PCK2 is linked to renal carcinoma.