Consistently, p-Erk+Olig2+p53Mutant-expressing glioma precursors expressed the markers for neural stem cells and transit-amplifying progenitors (TAPs), including Ascl1, Ezh2, and BLBP, but not more differentiated oligodendrocyte precursor cells (Fig. 7j)19,21,31. This evidence concerns the gene OLIG2 and central nervous system cancer.