OLIG2 and central nervous system cancer: Using the expression of mutant p53∆E5–6 protein as a marker, we identified early glioma-like clusters comprised of BrdU+Olig2+ cells in 8/14 (57.1%) brains from p53∆E5–6CKO mice compared to only 1/9 (11.1%) from p53∆E5–6Rictor∆/∆CKO mice (Fig. 8a–e).