Multivariate analysis of factors related to OS included age (≥ 60 vs. < 60 years), AML types (non-M3 vs. M3), risk group (high vs. inter vs. low-risk), the time-dependent variable for allo-HSCT (yes vs.no), ASXL1 (mutated vs. wild type), RUNX1 (mutated vs. wild type), U2AF1 (mutated vs. wild type) and SF3B1 (mutated vs. wild type). Here, SF3B1 is linked to acute myeloid leukemia.