TP53 and acute myeloid leukemia: CI < 1.0 for virtually all conditions (except two conditions for Molm13) indicates synergism between TPL and ABT-199 in both p53 wild type (Fig. 1e and Supplementary Fig. 1A, B) and mutant/null AML cell lines (Fig. 1f and Supplementary Fig. 1C–E).