To further confirmed the association between H19, hnrnpA2B1 and Raf-1, we analyzed the expression of H19, hnrnpA2B1 and Raf-1 in the primary colorectal cancer tissues and demonstrated the expression of H19 is positive correlated with Raf-1 (Figs. 6f, S9a and S9b). The gene discussed is H19; the disease is colorectal cancer.