H19 and Hyperglycemia: Additionally, knockdown of lncRNA-H19 inhibits abnormal differentiation of small intestinal epithelial cells in diabetic mice and elevated hepatic expression of lncRNA-H19 contributes to hyperglycemia in type 2 diabetes, suggesting its potential role in the modulation of type 2 diabetes (Zhang et al. 2018b; Shan et al. 2018).