Relative to normal saline treatment, exo-miR-375 agomir or exo-NC-agomir administration elevated E-cadherin expression, and decreased the expression of ENAH, Ki-67 and Bcl-2 in the tumor tissues, of which exo-miR-375 agomir led to more pronounced alterations (Fig. 7C). This evidence concerns the gene BCL2 and neoplasm.