In line with these observations, our results suggested that EA treatment effectively repressed DHEA-induced hyper-activation of mTOR/4E-BP1 signaling pathway in the skeletal muscle tissues of PCOS-like rats, indicating that EA alleviated insulin resistance in PCOS-like rats via inactivation of mTOR/4E-BP1 signaling pathway. Here, MTOR is linked to polycystic ovary syndrome.