We assessed CLL progression in male and female Eμ-TCL1 transgenic mice in 11 independent studies ([12,13,14,15] and unpublished data) regarding the percentage of CD5 positive B-CLL cells in the murine peripheral blood (% CLL) at six and 12 months, and the overall survival (OS). Here, CD5 is linked to B-cell chronic lymphocytic leukemia.