INS and Hypoglycemia: This raises a couple of questions, as follows: (1) is the CB’s participation in the counterregulatory response to hypoglycemia dependent on insulin levels?; if not, (2) can we see the same physiological responses to low glucose independently of insulin?; (3) can CB glomus cells sense changes in insulin levels?; if so, (4) can CB malfunctions induce insulin resistance?