PAET2 revealed a class II RNR protein induction of ~1.91-, ~1.71- and ~5.02-fold for the same cell infections and intracellular persistence time, while in the clinical PAET4, NrdJ induction was calculated to be ~6.17-, ~5.83- and ~2.90-fold higher after 24 h of intracellular persistence within the different lung epithelial monolayers. The gene discussed is NR2E3; the disease is infection.