First, hyperglycemia is known to stimulate the proinflammatory transcription factors, such as nuclear factor κB (Esposito et al., 2002), increase the expression of intercellular adhesion molecule‐1 (ICAM‐1) and neutrophil infiltration (Justicia et al., 2017) and lead to ischemic tissue damage. The gene discussed is ICAM1; the disease is Hyperglycemia.