However, no significant association was identified between overexpression expression of S100A4 and other clinicopathological parameters, including gender (male vs. female) (P=0.641, OR = 0.95, 95% CI: 0.75–1.19, I2= 0.0%), tumor size (>3 vs. ≤3 cm) (P=0.209, OR = 1.96, 95% CI: 0.69–5.62, I2= 84.2%), and smoking (yes vs. no) (P=0.673, OR = 1.08, 95% CI: 0.76–1.52, I2= 38.9%). This evidence concerns the gene S100A4 and neoplasm.