A number of studies on the improvement of depression in adults and theelderly by Qigong associate this result with the reduction ofstress-related signals received by the limbic system, in the hippocampus and in theamygdala, in view of the connection between mind/attention with a confirmed focusthrough therapeutic practice, which consequently demonstrates having an effect onthe secretion of the hormone responsible for releasing corticotrophin from thehypothalamus and, as well as from that adrenocorticotrophic (ACTH) by thehypophysis(47-48). The gene discussed is POMC; the disease is depressive disorder.