FOXM1 is a high‐risk myeloma gene with poor prognosis, FOXM1 was up‐regulated between GBM and normal tissues, and enriched in the GO term: cell cycle arrest, G2/M transition of mitotic cell cycle, negative regulation of stress‐activated MAPK cascade, suggesting that FOXM1 might be a potential gene in gliomas development. This evidence concerns the gene FOXM1 and central nervous system cancer.