The IFNγ‐regulated and 5‐AC‐inducible proto‐oncogene SBSN [12, 13, 14, 15, 16, 17, 18] plays a prosurviving role in the radio‐ and chemo‐resistant stem cell‐like compartment of some human cancer cells, and its aberrant expression is observed in several human solid malignancies where its presence is linked to tumor progression, aggressiveness, and poor prognosis [19]. This evidence concerns the gene IFNG and cancer.