For the patients with primary F2 diagnoses, the final NN model yielded a 22.5% subgroup (n = 18) with a highly significant linear correlation of r = 0.746 (p = 0.0004) between the global schizophrenia score and IgM levels, and a false-positive prediction error rate of 5.6%. The gene discussed is CD40LG; the disease is schizophrenia.