For example, Imai et al. (2013) reported that expression of MUC5AC in CRC decreases with increasing malignancy, and the loss of MUC5AC expression may be a prognostic factor for aggressive colorectal adenocarcinoma, which suggests that patients with high expression of MUC5A have a better prognosis. The gene discussed is MUC5AC; the disease is colorectal carcinoma.