A deep targeted resequencing of 122 genes in Dutch ulcerative colitis (UC) patients was performed and identified an association of rare variants in the MUC2 gene with UC in the Dutch population but not in the German population, suggesting a putative, population-specific role of MUC2 in UC susceptibility (Visschedijk et al., 2016). This evidence concerns the gene MUC2 and ulcerative colitis.