Based on the linear least square regression calculating method, the expression of CORO1C was shown to have a negative tendency with tumor purity (r = −0.475, p = 3.71e-22) and the level of infiltrating B cell (r = −0.193, p = 2.12e-04); meanwhile, CORO1C expression was positively correlated with the infiltrating level of CD8+ T cells (r = 0.487, p = 3.13e-23), CD4+ T cells (r = 0.145, p = 5.59e-03), macrophages (r = 0.19, p = 2.60e-04), neutrophils (r = 0.437, p = 2.20e-18), and dendritic cells (r = 0.563, p = 6.67e-32). The gene discussed is CORO1C; the disease is neoplasm.