AKT1 and hepatocellular carcinoma: MiR-342-3p inhibits IGF-1R-mediated PI3K/AKT/GLUT1 signaling pathway by reducing glucose uptake, lactate production, ATP production, and extracellular acidification rate (ECAR) and increasing oxygen consumption rate (OCR) of hepatoma cells to achieve the inhibition of cell proliferation (102).