KIF20A and neoplasm: Univariate Cox regression analysis confirmed that tumor size (HR = 2.086, 95%CI = 1.131‐3.848, P = 0.019), differentiation degree (HR = 5.299, 95%CI = 2.799‐10.030, P < 0.001), T stage (HR = 4.469, 95%CI = 2.112‐9.458, P < 0.001), N stage (HR = 2.630, 95%CI = 1.817‐3.805, P < 0.001), M stage (HR = 3.396, 95%CI = 1.661‐6.944, P = 0.001), TNM stage (HR = 2.520, 95%CI = 1.761‐3.608, P < 0.001), and KIF20A expression (HR = 4.457, 95%CI = 1.877‐10.579, P = 0.001) were significantly associated with worse prognosis in CRC patients.