The significantly lower number of tumor-infiltrating, I-A-expressing (p < 0.001, Figure 3(b)), and IL-12-producing (p < 0.05, Figure 3(c)) F4/80+macrophages and CD80- and I-A-expressing CD11c+DCs (p < 0.001, Figures 3(d) and 3(e)) indicated that MSCs alleviated capacity of antigen-presenting cells for optimal activation of T cell-driven antitumor immune response. Here, CD80 is linked to neoplasm.