The reduced number of tumor-infiltrating CTLs, Th1, and Th17 cells corresponded to the increased plasma levels of TGF-β and IL-10 in B16F10+MSC14d-treated animals, indicating the important role of TGF-β and IL-10 in MSC-mediated suppression of T cell-driven antitumor immune response. This evidence concerns the gene IL10 and neoplasm.