CD8A and neoplasm: Additionally, a significantly lower number of granzyme B-expressing CD8+CTLs were observed in the tumors of B16F10+MSC14d-treated mice (p < 0.05, Figure 4(g)), indicating that MSCs injected 14 days after tumor induction significantly reduced the presence of cytotoxic and proapoptotic CD8+CTLs in the tumors of melanoma-bearing animals.