Interestingly, the absolute cell number of Vγ9 T cells within the TIL population was reduced after zoledronic acid stimulation and, again, we observed an increase in gal-3 release after addition of zoledronic acid to cocultured cells as well as a strong intracellular gal-3 expression in tumor cells and TIL in this autologous system (Figures 8B,C). The gene discussed is LGALS3; the disease is neoplasm.