However, in BMDMs the increased induction of IL-10 driven by the Δmmpl7 mutant Mtb over WT Erdman was recapitulated by addition of DATs to WT Erdman infection (Figure 5B), thus suggesting that DAT overexpression on Δmmpl7 mutant Mtb actively induced expression of anti-inflammatory IL-10 produced by macrophages. This evidence concerns the gene SLC6A3 and infection.