The proliferation of BC cells was measured and it could be found that (Fig. 3c, d) in MDA-MB-231 cells, the cell viability (P < 0.001) and colony-forming ability (P < 0.001) were repressed in the oe-SATB2-AS1 group versus to its NC group; in MCF-7 cells, the cell viability (P < 0.001) and colony-forming ability (P < 0.001) were promoted in the sh-SATB2-AS1 group versus to its NC group. This evidence concerns the gene SATB2 and breast cancer.